one of three cute lil kindergarteners who save the world with special powers. Said powers include ICE BREATH and FLAMEY EYE THINGS... they were created from sugar, spice, eeverything nice, ans chemical X.
OH NO, that giant bunny rabbit ate my prize winning BIG ASS carrot.... somebodt call the Powerpuff Girls on that nifty blinking phone.
by Jim July 27, 2004
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Ayy bro did u see that powder puff girl on tha corner !?"

-ayyy lmao
by Cakhuiloz April 11, 2016
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One who is a twinkie. Acts annoyingly cute and innocent. Is vacuous, fakely fragile, and uses the word "like" in almost every sentence.
"Oh my god! I like, just broke my nail!"
"Whatever, you power puff girl."
by Zebliz March 19, 2006
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A gacha tiktoker on tiktok.
(p.s totally not made by puff..girls)
“puff..girls is a gacha tiktoker!”
by HHHBARKBARKHHHHHH November 27, 2020
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