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v. To decline to give self-incriminating information. Refers to the fifth amendment of the US Constitution, which states that no citizen "shall be compelled in any criminal case to be a witness against himself..."
Joe: Bob, did you ever do drugs in high school?

Bob: I'm gonna plead the fifth on that one, Joe.
by Gargouille July 07, 2005
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To withhold all information concerning one's actions while in a state of complete intoxication (similar to that which one would be in after consuming a fifth of liquor). Such withholding is an effort to protect one's reputation, but also could be due to the fact that the individual simply drank too much to remember what happened during the time in question.
Dan: "Dude, did you *seriously* hook up with Sandra last night? I thought you hated that bitch."

Steve: "I can't even remember what happened after we left the bar. I'm gonna have to plead the fifth on that one."
by Ti-na-na-na September 02, 2007
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When you have a potentially LOUD fart and you spread your butt cheeks to make it silent. Of course now it smells worse.
I can't wait for my spouse to leave the room, so i had to plead the fifth.
by Vese October 16, 2010
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An over used term to remove 'house of cards' charaters from a scandal debate.
"im going to put that governer on trial!"
"His going to plead the fifth, and you'll look a fool"
by meh3515 June 01, 2017
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