A rhythm game capable of making you feel all stages of grief at once.
The gameplay mechanics involve clicking circles to the beat of the music, and once you enter 4* difficulties you will start to develop tendonitis, RSI and carpal tunnel at the same time.
Me: I just took part in an osu! Tournament.
Friend: cool! How'd it go?
Me: well, I can't feel my wrists and also I'm in an ambulance
by Djchu March 21, 2019
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A term used in Karate

or

A popular rhythm game.
1. Fighter 1: Are you ready to fight?
Fighter 2: Osu!
2. Tom: What are you doing Simon?
Simon: Playing a game. It's called osu. Wanna try it?
by 123adi May 13, 2016
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(usually pronounced: oos )

A term used in karate or mixed martial arts schools meaning yes, hello, goodbye, and I understand. A general affirmative.
Teacher: Is everybody ready?
Students: Osu!
Teacher: Begin!
by Guildenstern14 November 12, 2009
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osu! is a freeware rhythm game originally for Microsoft Windows. It is written in C# on the .NET Framework. The game has also been ported to Mac OS X, iOS, and Android. Its gameplay is based on commercial titles including Osu! Tatakae! Ouendan, Elite Beat Agents, Taiko no Tatsujin, beatmania IIDX, O2Jam, and DJMax.

Despite the stupidity stupidity of some; it is pronounced Oh-Sue. Not OOS.
A: Have you heard that game, osu?

M: Yeah it's like guitar hero except you pick the songs.

A: Wow sounds cool. How do I say it?

M: Oh-Sue.
by Oh-Sue September 06, 2014
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A rhythm game by Dean Herbert where you click circles. It's also a game for problematic people and Anime Weaboos
Osu has not only wasted my brain cells, but it also caused me to have an addiction to anime and no friends. I can no longer call myself a normie.
by WebooTrash April 06, 2019
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OSU! is an open source music rhythm game developed by Dean Herbert at 2007. The game consists of four game modes: osu!standard, a circle clicking simulator; osu!taiko, a drumming emulator; osu!catch, a fruit salad catcher; and osu!mania, a key smashing synthesizer. For more info, you can visit: osu.ppy.sh
I heard that OSU! has become more and more popular.
by Jin6000 March 18, 2019
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A platform for dweebs and/or children to practice useful real world skills.
Steven: Wanna go out?
Dweeb: No, i'm gonna livestream Osu!
Steven: What for?
Dweeb: Heh...*le closes all crunchy roll tabs* a skill i can only show m'ladies ;3
by kakapoopooaccount December 07, 2018
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