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When you reach a level of intoxication where your speech turns into that of famed talk show host Oprah Winfrey. At this point in alcohol consumption everything is your favorite thing and needs to be announced in a loud voice. Being Oprah drunk is being equated with being the asshole of the party.
"Dude you ok?"

"No, I'm druuuuuuuuunk! Everyone's getting a text, you get a text, you get a text, everyone gets a text!"

"Your Oprah drunk"
by Chakaface September 29, 2013
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