A phrase coined by the British comedy troupe Monty Python. It is used to signify the arrival of something that is, indeed, completely different from whatever had been going on previously.

See also: Pythonesque comedy.
The llama is a quadruped which lives in the big rivers like the Amazon. It has two ears, a heart, a forehead, and a beak for eating honey. But it is provided with fins for swimming.

Llamas are larger than frogs.

Llamas are dangerous, so if you see one where people are swimming, you shout...

Look out, there are llamas!

And now for something completely different - a man with a tape recorder up his nose.
by NeNay July 04, 2005
Get a and now for something completely different mug for your cousin Sarah.
Usually a guy saying he's changed.
Mika: I ain't taking you back Corbyn
Corbyn: Girl I'm on something different!
by apersonisheretodefinestuff September 08, 2018
Get a on something different mug for your Aunt Zora.