A curse word (slang)

1.a despicable or very unpleasant person or thing.

2.a person or thing of a specified kind, especially one that is formidable, remarkable, or impressive in some way.
"that cover photo proves he is one talented motherfucker"
by Wxnterr September 03, 2020
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where guys call each other motherfucker when they greet each other. They are not being insulting to each other and it is a display of affection. The difference between this and an insult is in tone of voice and body language ect.
Man 1: hey I haven't seen you in a long time. You doing motherfucker?
Man 2: just fine. How are you doing motherfucker?
Man1: Great.
And that is an example of a motherfucker greeting.
by Deep blue 2012 November 12, 2009
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Mario Lopez haired slim Jim. Searches for big foot when goes camping. Turns on people with his snagged tooth. Tries to be a baller. Says he's succeeded. Would whoop sense into you with 10 in chode.
Sandy sucked the motherfucker named frankie chode yesterday.
by Męë November 22, 2016
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The pathological cell type identified in Bushcle-Lowenstein tumors. Buschle-lowenstein tumors are a rare benign penile tumor caused by human papilloma virus infection with giant tumor growth but only local tissue destruction; may result in urethral fistula formation. The tumor resembles a cauliflower-like mass. Diagnosis is achieved via collecting cell scrapings of the mass with subsequent identification of motherfucking cells (MFCs) on diagnostic electron microscopy. There has been considerable debate regarding the exact nature, etiology, and treatment of these lesions. Like oral florid papillomatosis and epithelioma cuniculatum, Buschle-lowenstein tumors are considered to be a regional variant of verrucous carcinoma. MFCs have been observed on samples involving the penis, vulva, scrotum, bladder, and perianal or anorectal regions. Management of these tumors is controversial, but involves chemotherapy, radiation, and surgery.
The motherfucking cell was identified on diagnostic electron microscopy.
by ProfPath March 25, 2017
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