A nasty chafing of the nut sack region that causes the inflicted individual to walk in a monkey-like state.

Often caused by heavy sweating of the nether regions, combined with tight, ill-fitting clothes and excessive 70's style disco dancing.
From the look of that dude's apish stroll, he must have a nasty case of the monkey balls.
by pacoGAME May 28, 2009
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One of the best game cube games I have ever played
Monkey Ball is one of the best video games I have ever played
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A game developed by Amusement Vision, a subsidiary of Sega, and released as a launch title in 2001 for the Nintendo GameCube where the player is tasked with getting a monkey trapped inside a ball into the goal. However, moving the Control Stick doesn't move the monkey, rather, it tilts the stage. This game is actually a remake of a Japan-only arcade game, simply titled Monkey Ball.
Expert Floor 7 is the hardest stage in Super Monkey Ball.
by Gestersmek September 13, 2014
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something being so bad that it sucks monkeys balls
jill: my boyfriend dumped me

Janet: that sucks monkeys balls

John: I lost my job

Jack: that sucks monkeys balls

that guy/girl sucks monkeys balls
by YeahIWentThere August 24, 2010
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something thats really messed up or gruesome,or unfair
man i got fired today and my rents due, this is some monkey ball bullshit !
by samielmorningstar December 26, 2011
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