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Metropolitan Innundation Syndrome, or MIS, has two main manifestations.

The most prominent occurs when someone of rural or suburban origins travels to a large city. Symptoms include disorientation, slow reactions (as they are unused to the faster pace of life), respiratory problems (from polution), hearing loss and/or tinitus (caused by city noise), and eye strain (from excessive light exposure).

The second manifestation occurs when a city-dweller travels to suburbia or a rural area. The primary symptom in this case is boredome, and subsequent substance abuse or destructive behavior.
Type I: WTF? Where am I? All the streets look the same! I can't think with all this noise and light!

Type II: Dude! There's no Starbucks here! Let's get drunk and burn stuff.
by fox August 08, 2005
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