A man with feminine qualtiies who still likes women, or, to put it more crudely, a male lesbian.
Dang, that kid is such a mesbo. I hate how all the ladies hang on him.
by rtil June 30, 2005
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(n) A male acting as a female lesbian in a chat room, or other internet relay medium, in an attempt to pick up women. Most notable by speech patterns, or desire to find any bi/lesbian woman in a particular area.
"I'm tellin' you, anyone that thinks every woman on the 'net is 18 and bi, AND tries to pick them up, is a mesbian."
by Bystrick March 22, 2003
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A male lesbian, a man who acts like a dyke.
That mesbian, tell him I said no dance offs.

Chris Doman might be a mesbian, sources are unconfirmed.
by ChrisDoman March 22, 2012
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A male who pretends to be a female online just to get the attention of other females who happen to be real lesbians.
"I fucking hate mesbians"
by Wen LLH November 14, 2016
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A women who love and adore great actress Meryl Streep.
"I <3 Meryl Streep"

"I see. So you're a lesbian"

"Nope. I'm a mesbian"
by kmc64 January 14, 2012
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