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1. Connor F. is on the verge of MDS

2. Hey, how's MDS therapy been? I'm a survivor myself.
by ChillChill May 16, 2011
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short for Manu Down Syndrome; A sexually transmitted disease (STD) that can only occur when intercourse has been achived with Manu Jordan. Effects are blahblahblah..
Ohh man.. George caught MDS and now we can barely understand him.
by BillaBobb April 22, 2009
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Mds- is short for muddaskunt or in other words your mother cunt

It is Caribbean slang used in cursing someone out stink 🇻🇮🇻🇮🇻🇮🇻🇮🇻🇮
You muddaskunt really pissing mii off now

Get from here mds
by Therealpussman June 18, 2019
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match dat shi- meaning put in and ill put in to smoke
aye cuh mds”

fasho ill cop a g and u cop a g”
by di3rn May 01, 2021
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MDS stands for michael defense squad. it's a groupchat on twitter made of 4/4 5sos stans. it's a groupchat where everyone's opinion and identity is respected. honestly the best groupchat on twitter, full of love, support and hyping each other up.
"was feeling a bit sad today but mds cheered me up🥺"
by cliffordlftv August 13, 2020
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MDS is another saying for OMG (Oh My God)!!
MDS! I’m so excited for the party tonight!!
by AG2021 August 18, 2021
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MDS (mask derangement syndrome) is a newly diagnosed disease that causes irrational fear of face coverings causing such side effects as belief in a deep state and the belief that anyone who doesn’t share conservative political beliefs is a socialist which basically makes them non human and their lives irrelevant. It’s an awful affliction. No known treatment has been discovered for this disease but using reason and logic when communicating with someone who has contracted MDS only tends to worsen symptoms. Please help raise awareness of this illness.
Karen just said she’s worried that wearing a mask will cause permanent lung damage. Karen has severe MDS.
by Dr.knowledge8888 August 27, 2020
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