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the intravenous injection of a drug. which means using a needle to get a drug into your vein, to absorb it through your bloodstream. a lot of drugs can be taken this way, the most commonly associated drug being heroin.
Layne accidentally overdosed by mainlining heroin.
by two blue lights November 10, 2008
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Jun 12 Word of the Day
Solarpunk is a movement focused on a positive, ecological vision for a future where technology is used for human-centric and ecocentric purposes. It is a literary, artistic and aesthetic sub-genre and is also closely tied to eco-political activism. Solarpunk narratives have a distinctly positive and utopian foundation in contrast to the often dystopian visions found within other "punk" science fiction genres.
Solarpunk is a literary movement, a hashtag, a flag, and a statement of intent about the future we hope to create.
by wix99 September 20, 2016
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2
The act of binge-watching or binge-listening all episodes of a podcast or all episodes in a season of a TV show without breaking for sleep.
Mackey: Where were you last night?
Buddy: Aw, man, I was mainlining "Sense8." After the second episode, I was addicted!
by GypsyBowl July 05, 2015
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3
the act of taking internet lingo and applying it to real life conversation

matt: I walked by a group of kids taking a test and said, "fucking scrubs."
joel: dude, you were totally mainlining.
by Taxt April 16, 2009
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