Guy 1: Man! Did u see what Zach did to Andrew?

Guy 2: Yeah! What a soops lose!
by CABLEGUY1212 June 23, 2016
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Being in the the state of confusion and absolutely going bonkers. The person who says this phrase usually states it in a tone where they are rather stern and will get ready to square up on the spot (known from experience).
Shannon- Sweetie, are you alright? You're strangling the dog again!

Bertha- I'm about to lose my marbles!
by Anti-Vaxx Parent May 10, 2019
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Similar to 'no skin off my nose'
I don't think they like your idea but don't lose skin over it.
by Zpw2711 June 14, 2017
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Losing in life as a result of Booze intake. Covers literal loss as well as more figurative varieties.
I got really drunk last night, and lost my wallet, the respect of several peers and now have hideous regret and life-debilitating hangover. What a textbook case of Booze Lose.
by ajsmith June 10, 2012
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