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Bob~ "Hey dude, remember that funny thing i did last night?"

Jack~ "yeah, LMSO"
by A7Xrules112 January 07, 2011
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Laughing My Socks Off

A politer way of saying "lmao"
Jake: Did you hear? A cat lady moved down the street!

Tom: LMSO!
by Neko-chan November 21, 2007
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Laughing My Shit Off:

When you have a little piece of crap dangling from your rectum and you laugh to get it to fall.
I spent over twenty minutes on the toliet laughing my shit off.
by chaoskron May 06, 2004
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GUY 1 (after seeing a funny picture): LMSO! …laughing my shirt off.

GUY 2: Too bad you're not a buxom female.
by themagicalnegro May 18, 2010
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Laughing my shirt off - a variation of LMAO. Often followed up by "AFITAC!" "and feeding it to a cow!" as popularized by the British gangsta-gypsy-rock band Larrikin Love's song On Sussex Downs.
Ed is so Rubbish that I was LMSO AFITAC!
by K8 'n' Sandy January 13, 2007
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When one laughs their shit out <3
" hahahaha i think i just laughed my shit out "
" wow my shit has been laughed out "
" let me check, i think i shit my pants "
" lmso mayyyyne "
by Latique December 16, 2007
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Acronym, Meaning Laughing my Sh** out.
If you're on a date 'oh Look baby I laughed so hard I sh**'
"LMSO!'
by P.B.B June 08, 2007
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