7
Girls who hang around a fraternity in hopes of finding a boyfriend/husband. Usually they find neither but end up geting fucked by numeroius members of the fraternity.
I hope this semester we get some new little sisters!
by yo mama September 16, 2003
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10
A younger female sibling that can be annoying as hell and you probably fight a lot with. But no matter what's going on, she will always be by your side wether in good or hard times and help as much as she can to make you feel better when you are down.
Although my little sister makes me going crazy literally all the time, she's the best one of them all
by AkaLee November 21, 2016
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11
the most annoying little losers in the world who look up to you and wont stop leaving you the fuck alone!
little sister follows you tell her to fuck off, wont stop tell parents older sibling gets blame.
by J'aDoRe JUiiCY September 25, 2006
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12
the victim of an over protective male influence known as a "big daddy"
Zaxq: poor shelbie has turned into a little sister!
Drew: I Know kyle's being such a big daddy!
by xXPyramidheadXx3 February 17, 2010
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