To lay hands on someone is to want to fight someone. As in lay your fists on their body to create pain.
"He's talkin shit bout my grandma, so i'm bouta lay hands on a nigga."
by J-Thizz May 14, 2008
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Bitch you better stepoff 'for i lay hands on you!

or

I dare that ho to lay hands on me!
by Mizze July 10, 2008
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verb. to acquire or gain posession of
There is no way I'll be able to afford that concert ticket unless I lay hands on some cash.

Were you able to lay hands on a copy of that CD?
by hardcore_2031 July 05, 2005
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an ability commonly used by paladins in role-playing games, that heals you on someone else for a large amount of health. usable generally once every in-game day.
that paladin was almost dead, but he used lay on hands, and now he is okay
by Dalsson January 17, 2008
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A laying down of a hand is a phrase that represents physical force use to coerce or as retribution.
The whore was not paid so the pimp had to lay down the hand.
by limitofone July 26, 2009
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