Please, as translated into Japanese. Commonly used with "aishite" which means means, loosely translated "love me." So "aishite kudasai" means "Please love me." Also found in the Dir en grey lyrics of the song "Merciless Cult."
"ai shite kudasai kono chi mo sono imi mo
ai shite kudasai kono hi ni kono kachi wo"

English translation:
"Please love me, this blood and the meaning
Please love me, this day and this value."

-Dir en grey, "Merciless cult"
Lyrics and translation from songmeanings.net
by Kelsey D May 26, 2008
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Literally means "Please Stop" in japanese. And these "UwU" girls think this is a sexual word. Lmao now i remember my uwu phase in 2018.
Man: *touches girl uncomfortably*
Girl: Yamete kudasai! Im a minor..
by N3K0-! July 08, 2021
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Yamete kudasai usually means something along the lines of, please stop it. can usaly be heard in anime when female human creatures are mating with male human creatures.
No not there! That place is highly restricted for public view! no! please! YAMETE KUDASAI!
by ARandomghumanbeing December 02, 2017
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