Extreme misfortune. The undeniable fact that the multiverse has something against you.

v. collectively or individually finding someone/something to blame for a problem, as opposed to brainstorming which connotes finding solutions to a problem

n. the act of finding someone/something to blame for a problem

(from a TV ad for HD television)

When someone so T H I C C walks up that your dick gets so hard it rips through the fabric of your pants

Extreme misfortune. A tendency for a person to have everything that could have gone wrong go wrong; the undeniable fact that somehow there is an unseen force directing one's bad luck.