A verbal exclamation used when a large (and often clumsy) mistake has been made, such as dropping a wine glass on the floor, backing your car into a telephone pole, or forgetting a girlfriend's birthday.

Can also be used in an noun sense, as an affectionate name for a clumsy friend.

The phrase is intended as a suitable, non-vulgar replacement for the more commonly-used exclamations in this context (eg, "Son of a bitch!", "Fuck!", etc).

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.