A chromosome which is genetically responsible for the homosexual tendencies of a person.
Hey Gonzales, that guy looks a bit fruity to me!
Don't be judgmental, Rastenborsky. Can't really blame the mate. He's got one too many homosomes.
by Pedro Chacha May 16, 2008
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The chromosomes of a homosexual. Usually used to talk about a gay person.
Did you see Jerry wearing those tight pants today?

He's got some serious homosomes going today.
by Hikaru-Hikari2 November 16, 2007
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The genes that homosexuals, lesbians, transgenders, and queers carry in their bodies. Or just faggots in COD lobbies...
These retards must have HOMOSOMES in they blood cuuuuuhhhhh.
by Taco Monkey MD June 07, 2020
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