A female that gets on your nerves and/or does annoying things
"That girl that just bummped me in the hall is such a heffa"
by solo77 September 27, 2013
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a fat ass person who likes to eat
damn heffa you ate three whoppers and you are still hungry?!?!?!
by pringdawg February 03, 2003
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A woman who knows better than to do something, but does it anyway.
That heffa wore my shirt after I specifically told the heffa NO!
by Gretchen March 21, 2003
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a female that does not realize that her actions/words are not "cute".

Please refer to 'cute'
That heffa needs to shut up before someone slaps the taste out of her mouth
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Any female who is out of line in what ever way and especially those who pisses me off
That heffa that cll my office fussing because she can not get her money back
by Theonlyone January 20, 2004
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A nicer way of callin a woman or gay man a bitch
Damn, she is a real heffa.
by dino90404 November 27, 2010
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