This is the nickname of a person who is amazing at everything, especially: school, sports (football and wrestling), guitar hero 1&2, and life in general. Not to mention all of the ladies he gets.

The Gus Bus is Gustavo Sorola, the voice of Simmons of Red vs Blue, but the term Gus Bus came from a comic strip from Penny Arcade. (PAX)

A fictitious "bus" named after Auburn's current head football coach, Gus Malzahn, which that could mean any of the following:

1. The Auburn football team
2. The vehicle carrying the Auburn football team
3. A vehicle carrying a bunch of Auburn football fans
4. A general mood of optimism among Auburn fans

A pedophile/ older man that likes abusive behavior in his relationship with his prepubescent counterpart.

The act of going to Wembley Football Stadium on the 'Gus Bus,' specifically used by Sunderland AFC fans when they reached the Final of the Capital One Cup in 2014 as their manager was Gus Poyet at the time

A figurative reference towards the depressed mood one is in, due to the alienation of his/her peers.