It means that a person must go and fuck himself and piss off. Found in Scottland.
Do you want to become part of the church?
"Get 2 fuck ya wee prick."

John have you done your home work?
"Get 2 fuck you shit stained balls."

Hi would you be my god?
"Get 2 fuck you bible basher."

by Vinceonorp666 February 24, 2009
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Often heard in movies where the characters are Italian Americans living in New York.

It simply means that you don't believe what someone else said.
Henry Hill: There it is, you see that Mike? You see that Helicopter? See it right there, right infront of us there? I think it's been following me all morning.

Mikey: Get the fuck outta here! What are you, nuts?
by SoySauceBill October 02, 2009
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Def.1 To express disbelief in something someone has just said.

Tom; "Did you hear that jamie gave me crabs."

Eddie; "Get the fuck outta here!!"
by EddieLee October 14, 2007
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The proper response to someone who has overstayed their welcome.
-What time is it?
-It's Get The Fuck Out O'Clock.
by Barbie T September 08, 2010
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when one person wishes to eject another person out of a room during an intense conversation in an awkward housing situation.
by district J July 05, 2010
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