To skin up a joint of marijuana.

to begin seriously doing what you need to do;
to begin to get serious; to begin to negotiate or conduct business;
to start talking about the subject to be discussed;
to apply oneself to serious matters; concentrate on work...

a band from l.a. really good too

One usually gets down to business to defeat the Huns

to get yourself motivated and to do it efficiently

1.If said “I’m getting down to business tonight” means that you are going to jack off tonight or masturbate

2. If two people are involved “ we’re getting down to business tomorrow” then means y’all having sex

This saying is used in reference to having sex either with someone or by yourself.