14
when youre trying to holler at a girl but you do something to totally ruin your game
i approach sandy with a drink in hand and end up tripping and spilling half the drink on her shirt.. my friends greet me with a "game over" when i return
by bay resident December 07, 2005
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15
the aftermath of staying up all night playing video games,with symptoms of a hangover the next morning.
i stayed up all night playing uncharted 2,and went to bed at 6 a.m. woke up at 2 with a gameover.
by ronda howard January 08, 2010
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16
The hellish headache after playing 7+ hours of video games.
1: Dude, I have the worst gameover.
2: Oh damn, how?
1: I beat Dead Space 2 on Zealot overnight.

2: Jesus bro, thats hardcore.
by OrnateCocoapuff February 03, 2011
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17
When you beat someone in any type of situation. Also an exclaimation when you beat the shit out of some asshole. Or when a situation is just outta hand and you don't want to deal with it anymore.
Give it up bitch, game over.
GAME OVER MOTHER FUCKER!
This is game over for me, I'm out.
by grrrinator October 27, 2004
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18
Phrase used to describe one who has consumed far too much liquor and is therefore reduced to a drooling, snoring, unconcious lump who may or may not end up vomiting on themselves or other people later on in the evening. May sometimes lead to boot and rally, pissing in the fridge, or other drunken acts which will undoubtedly not be remembered in the morning. See ptfo. This is the most opportune time to attempt such daring feats such as teabagging, giving a flying squirrel or other humiliating acts.
Dude, check nick out, Game over.
Woah, did nick just boot-n-rally? i thought it was game over! add another tick to the boot-n-rally tally.
by Ry-Lo September 17, 2007
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19
When you finally end it completely... you’re a swallower & even you won’t swallow anymore of their bullshit.
Ohhh... so you like to play games...?

Lol... sorry baby, I was the real deal... don’t wanna play that kinda game . game over.
via giphy
by java804 March 17, 2018
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