Usually a woman or man who is a self centered (bitch) that just cannot be pleased and how their place in society somehow outranks yours.

In the workplace, its the snob that blames other people for their problems and how its hindering their work...

And of course the uppity/stuck up brat (read- bitch) that just won't shut up about how her relationship with some random dude is better than yours

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.