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"fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"
by Anonymous November 10, 2002
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1.) A shortened form of the phrase "Indeed, that is a prodigious idea, my African-American brother!"
Would you desire some more orange flavoured soda?

fo' shizzle my nizzle!
by Manawski March 30, 2003
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3
"I concur whole-heartedly, my African-American brother"
Hello, wouldn't it be great to go for a drive in my 1964 Impala, while drinking a 24 oz alcoholic beverage, to attempt to copulate with members of the opposite sex?

"I concur whole-heartedly, my African-American brother"
by Jimmy J April 07, 2003
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4
for sure my nigga - derived from our friend william shakespeare
"fo shizzle or no fo shizzle that is the quizzle my african american bizzle"
by Dudette9 May 22, 2005
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6
An abbreviation of the Latin phrase, "For Shegro, My Negro."

Although modern linguists are unclear on the definition of the word 'Shegro', it is widely believed that it is related to the worship of the Roman Goddess Goddamnatsonehugebitchia. Certain daily activities were thought to cause the goddess to increase further in size; therefore, these activities were conducted 'for shegro.'
"Yo, you wanna go to the liquor store for a fifth of cat piss?"
"Fo' shizzle my nizzle!"

(Or, from the ancient Latin)

"Come hither, O Dumbassitus Putridus! Let us away to the market of bottled lusciousness!"
"For shegro, my negro!"
by Edgar Allan Poo September 07, 2015
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