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fo shizzle my nizzle translates into "I will definitely acquiesce indubitably in the said activity such as drinking cool aid, grape soda, orange soda, KFC, watermelon, waffles, and various other food items".
Boo: Yo, would you like to participate in the consumption of Kentucky Fried Chicken, while consuming a 40 oz alcoholic beverage in the back of my vehicle that has the bass so far up that whenever I commute near a seismographic station, there seems to be a 10.7 on the Richter scale in Ethiopia.
La Fawnda: Fo shizzle my nizzle.
Boo: Well, that sounds swell to me. Let us hop in and endear in the lovemaking in the opposite sex.
by kevk77 March 15, 2009
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17
Originated in medival England in the 17th century, this phrase has changed in meaning completely, from the orignal shorthand denotation of "Alas! An advasary has come upon us! To the catupults!" to the modern definition of "Please grease up my penis."
Old: Bartholomew, the dastardly barbains are attacking! Foe Shizle mine nizle!

New: Bitch step up! Fo shizzle my nizzle!
by Darky April 09, 2003
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THE REAL DEFINITION!!!

Snoop Dogg did NOT originate the colliquialism of adding the suffix' -izzle, -eezy, -iggedy and so forth to common everyday phrases. If you actually know your hip-hop history, this type of language originated from "Double Dutch Bus" by the Gap Band. Download it and listen. Frequent examples of such rhetoric are sprinkled across the track.

However, to the credit of Snoop Dee-Oh-Double-Gee, he took something retarded and made it sound FULLY SHICK M8!

"Dizzuble Dizzutch, the Dizzuble Dizzutch!"
by R. Soul October 24, 2003
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20
A modernized and extended version of the infamous Shakespearean Hamlet line, "To be ... or not to be?"
"Fo' shizzle ... o' no' fo' shizzle? Dat be the quizzle, my south-central British nizzle."
by HootieFoo June 05, 2003
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