Top definition
A slang word for male masturbation. It refers to your 5 finers on your penis, hence 5 on 1.
Hey man, i'm horny, i think i'm gonna go do a lil 5-on-1.
by The Pimp February 03, 2003
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Jun 24 Word of the Day
An exclamation made when your friends or family are teasing you to a point where you can't handle it anymore and a hissy fit is in order.

Derived from a YouTube user's famed outburst following Britney's lackluster performance at the 2007 VMA's.
Sarah: 'OMG Susan, I can't believe you are wearing the same skirt as yesterday. Oh, and by the way, EVERYONE knows what you did with Kevin on the weekend. Plus you look a little fat, are you retaining water?'

Susan: 'LEAVE BRITNEY ALONE!'
by Billy Chickenhole September 15, 2007
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2
another definition for yankin your crank
My girlfriend wouldn't put out again so I had to go play some five-on-one.
by Doyle November 14, 2003
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3
What G-Unit members do to Fifty Cent when they are horny.
Hey Fitty, here's your 2 quarters, bend over, time for a Five On One...
by TruthMaster August 30, 2006
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4
A term for masterbation. As in you are playing five against one.
Where is Johnnie?

He is watching some midget porn and playing five on one.
by Nick Franocne September 13, 2006
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