1. Ese- As in "S" in Spanish for Southsider.
2. Used as a slang term in today's world as meaning buddy/friend.

3. Only used by Hispanics. If used by other ethnical groups, it might be found offensive. Just as the term "nigga" is only supposed to be used by black people, "ese" is only supposed to be used by Hispanics.
"Ay, Ese. What's up?"
or
"Is that ese going to hit up the party?"
by termteller May 14, 2009
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ese is a spanish word wich means "that one" but young mexicans have changed it meaning for "you"
it has nothing to do with surenos.
ese hombre es feo
that man is ugly
by El Padrino August 3, 2007
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The main word in a really funny joke from Comedy Central.
Mexican: Hey ese
White Guy: Why are you calling me a term paper?
Mexican: ?
by My_Name_Here January 25, 2005
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the letter S in spanish...
basically some of the previous definitions of these words are correct, such as 'homeboy,' 'foo,' etc.
but the S stands for southsider...
S=13=trece=crip related
where tha fuck you from ese?!
by G'd up loccstor July 11, 2005
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Linguistically, this word has a complex origin. In simplest terms, "ese" is derived from the Greek "es" meaning "is" and "e" meaning one of Spanish-American heritage. In more complex terms, the word is derived from the Latin "E", meaning "referencing one who is believed to be spanish" and "se" meaning "american".
"You're going down, ese." - Pearl
or
Ricardo: "Yo ese, good to see you made it 'cross the border."
by Bilqis Shambles September 29, 2007
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ey ese wassap you bitch
ese r pussy?
by PeterMan February 10, 2004
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