1. The thing you always died of in The Oregon Trail.

2. An inflammatory disorder of the lower intestinal tract, usually caused by a bacterial, parasitic, or protozoan infection and resulting in pain, fever, and severe diarrhea, often accompanied by the passage of blood and mucus.
Lisa died of dysentery. She can no longer continue the journey.
by Raym November 16, 2005
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You shit until you die
The four horsemen have decided your fate with death from dysentery
by The4horsemen October 10, 2019
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From the greek "dys," meaning sick, and "entera," meaning stomach.

This is the ancient way of saying belly hurty
Bruh 1: bruh
Bruh 2: yuh bruh?
Bruh 1: belly hurty bruh
Bruh 2: you mean dysentery you uneducated rapscallion
by 69bruh69 November 04, 2019
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A modern social disease whereby the afflicted have an uncontrollable biological need to shit out all of their menial mental musings.
Twitter whores should seek professional help for their cognitive dysentery.
by TNunnster February 06, 2010
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The condition experienced by witty and intellectual Urban Dictionary contributors whose entries never make Word of the Day. Instead, many obnoxious and boring entries are published, thus causing the intestinal pain and diarrhea associated with Urban Dysentery.
An email from Urban Dictionary containing the Word of the Day awaits me each morning on my phone. Today's word is Fart Enthusiast. Another day is ruined by Urban Dysentery.
by Lamb Lamb December 04, 2010
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