Top definition
A drug user who gains pride and purpose from taking a wide assortment of drugs, especially the endless variations of tryptamines and phenethylamines. Drug Twinkies generally view their drug use as profound mental exploration, and will harp on comparing the different psychonautic possibilities of various drugs.
"I just want acid, not any of that obscure drug twinkie crap."
by backfisch December 26, 2004
Get the mug
Get a drug twinkie mug for your daughter Larisa.