Refering to someone with Downs Syndrome - so really should be "downsie" It is a genetic condition that is increasingly common the older the mother of a child is when she falls pregnant. Downs Sydrome is caused by non disjunction of the 21st chromosome (humans have 23 pairs of chromosomes - each parent supplies 23 chromosomes to the child getting a total of 46) which means chromosome 21 in the mother has not split like it should when making sex cells (gametes) and the child ends up with 3 copies of chromosome 21 compared to the usual 2. Some characteristics of downs syndrome include:

Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Short neck
Small head
Small oral cavity
Short, high-pitched cries in infancy

Sufferers of Downs Syndrome are ussually smaller than their normal peers and their physical and intellectual development is ussually slower.

It’s an acronym standing for Can’t Remember A Fucking Thing. It’s usually used to describe embarrassment at being unable to remember someone (CRAFT moment); going onstage as the lead in the latest theatrical performance and your mind goes completely blank (CRAFT situation); the next morning after a night when you got pissed as a fart and woke up in bed cuddling a traffic cone and a string of fairy lights wound round your prick.

A derogatory term for someone with downs syndrome. a insult to someone who may act like they have downs syndrome, or just a dumb fuck

someone with down syndrome

A person with down syndrome.

Downy refers to someone with down syndrome, but when shortened to downy it is to be use to describe someone who is weird or says stupid shit a lot.

slang for a person with down-syndrome