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used to refer to something painful/dangerous/regrettable/otherwise negative associated with doing something you have voluntarily chosen to do and therefore implicitly accept the possible risk of.
>John: "Sorry if that round of tequila shots I ordered at the end of the night pushed you over the edge."
>Humberto: "Haha, no biggie. Cost of doing business with you man."

In this case, "doing business" refers to hanging out with John. the "cost" is the risk of getting too drunk because John likes to order tequila shots. Humberto is saying that by voluntarily hanging out with John last night, he implicitly accepted the risk of having a tequila shot served to him that may not have been a good idea but that he, in his intoxicated state, may consume anyways.
by reezydos July 13, 2014
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Apr 27 Word of the Day
A horoscope so bad that it strikes fear into the heart of the reader, rendering them unable take action or make a decision on anything or to even leave the house. This is caused by a paralyzing fear that those actions or decisions may cause the predictions to come true.
After reading "There is a lot of uncertainty around financial transactions and investments right now, and the wrong decision could result in dire consequences" in his daily Horrorscope, Edward climbed back into bed, pulled the sheets over his head and remained there for the rest of the day.

Edward only had enough gas in his car to get to the gas station but was not sure if he had enough money in his account to pay for gas. His cell phone service had been cut off because his payments were in arrears, and since the only way he could be sure he had enough money (to pay for gas) would be to call the bank, he felt it best to hide in bed and hope his horoscope for tomorrow was more positive.
by Edward Albee Deavers April 28, 2011
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