to tell someone to stop bullshitting; when someone is caught in a lie or you don't believe a word they are saying at the moment they are saying it.
I told Pichi to clean it up when he was caught telling everyone he was single instead of married.
by hersh12061 November 17, 2007
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When you show your man who thinks you are hot him you are not wearing any panties forgetting her "keys and he wants to screw your brains out but he can't do anything at the moment as he is working so he cums in his pants. This is what you call the situation "Clean Up on Isle 12".
After she walked by and lifted her dress up to show him she "forgot" her panties, he requested a napkin as he had to do a clean up on isle 12.

Forgetting ones' "keys" can cause Clean Up on Isle 12 issues in the office.

See defination "keys".
by jessikka_rabbitt December 07, 2009
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Something Gretchen from Bob's Burgers says when she's turned on by a cop
"Clean up, aisle my panties"
by D-Monkey March 02, 2018
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to clean, when everything is clean, the need to clean excessivley.

NOT A ACTUAL MEDICAL TERM, AT THIS TIME.
husband: what are you doing now?
wife: cleaning the inside of the bleach container..
husband: you have a bad case of C.C.U.D. (COMPULSIVE CLEAN UP DISORDER)
by the future doctor May 16, 2011
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Used in terms to someone having verbal diarrhea (chatting to much) or chatting shit (telling lies). The acknowledgment of the lies or the constant talking comes when a person says 'lets clean that up' and follows it with a hand gesture of cleaning a table. Used as an insult. First used in Newcastle, England.
'Sarah was chatting some shit today, after a while it got so messy, it got to a point where i had to be like....Lets clean that up!'
by G dawwwg February 22, 2012
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When your girl's on top and you pull out, finishing on your stomach, shout this to make her clean it up. A reference to Star Treks popular phrase "Beam me up, Scotty".
*cum noise* oh shit there's cum in my belly button, CLEAN ME UP, THOTTY!
by My neighbour to the north April 14, 2019
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