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synthetically or semisynthetically created drugs that are used rereationally. basically man made drugs created in a laboratory or some clandestine drug lab.

examples include lsd, mdma(ecstacy), methamphetamine, heroin, pcp, ketamine, several research chemicals (2ci, 2cb, 2ct7, DOM, DOB, DOI, 4-HO-DiPT, DiPT, 4-HO-mipt, several pcp analogues including pcc, pce, tcp, just to name a few), and finally various pharmaceutical drugs such as dxm, benzodiazepines, and various synthetic opiods including fentanyl, hydromorphone, oxymorphone, hydrocodone etc.
I quit using chems a long time ago. Now all i do is smoke weed, and indulge in the occasional mushroom trip.
by psychonautical October 15, 2006
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May 2 Word of the Day
when you've done something so cringe you can't stop replaying it in your head and it stops you from getting on with your every day life
Dan: bro why have you been staring into space for the last hour doing nothing?
Me: bro i have a chronic cringe from what happened earlier I can't concentrate
by finesseeeee March 01, 2019
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3
someone whose gold 3 at league and short and really bad at apex
DAMN! This guy must be a "chem"!
by CJ the gayest November 14, 2020
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4
Dude, that is so chem.

Negative form: chemless
ex. You're chemless, man.
by a techie March 25, 2006
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6
the pasty gunk in the crevice of your ass when you do not shower for a few days

I scratched my ass, and there was chem on my fingers.

Go drink a bottel of chem you stupid asswipe.

by Kayla Thy Great January 09, 2007
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