Like "before I/we forget," "by the bye" means the speaker (or writer) is going to change the subject. It comes from "by" (meaning "near") "the bye" (the closing, where we say "goodbye.") So it means, "before we say bye, let me also tell you...."
"... and that's all I heard about Brenda and Eddie. By the bye, have you heard from Brenda's friend Billy?"
by Wordslinger for Hire November 27, 2013
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This is a play on the phrase by-and-by which means: some future time or occasion.

By changing the spelling it implies that we are saying goodbye until some future time or occasion; til later on.

This is an especially useful phrase when you want to say goodbye to someone that has passed away.
Yo man, I miss you...I'll catch you in the bye-and-bye.
by abrupto12 July 02, 2009
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what i would very much like to say to George H. W. Bush
Oh my god why did Bush get re-elected? can't i just say bye bye to that dumbass hick?
by yungbuck4ever April 28, 2007
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When something you say can go both ways, either good or bad, like a bisexual.
Alex: Hey, I'm Bout to have this one girl come to my house, but I never met her before.
Mike: Really? Are you nervous?
Alex: I dont know man its a bye bye.
by Alex Palmieri March 09, 2009
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Used as a responding word, like "lol, "lmao" and "omg I can't even". Figuratively meaning that your leaving, like you can't deal with what has been said.
Requis: "Sometimes I wonder when you'll stop saying "BYE""
Felicia: "OMG BYE"
by moistpossum December 03, 2016
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A simple way of concluding a conversation.
Person 1: Okay, talk to you later! Bye!
Person 2: Bye!
by fhk x3 April 02, 2016
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