1. When someone's face is ugly to where it looks like someone's ass...

2. When you hallucinate thinking everyone has ass face...
Guy1: Damn! She's sexy but she has buttface syndrome
Guy2: Shut the hell up, she's born that way

Guy1: Everyone's faces look like asses
Guy2: Get off ecstacy you moron!
by fakename06 October 8, 2018
Get the Buttface Syndrome mug.