A girl whose lack of worth is not outweighed by the fact that she is willing to offer her rectum for hard anal penetration.

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.

A whore who likes to take it up the butt very often.

butt-skank is an insult,
it means disgusting, filthy, ass.