When you're really close with a member of the opposite sex and would like to date them but they refuse to date you because you are too close and they wouldn't want to make anything awkward between the two of you if the relationship didn't last.

You have best friend syndrome if...
1) You hang out with the person of your dreams more often then your friends. But ARE NOT dating.
2) They ask you to take them to an STD test or a gynecologist appointment. Or go with them as moral support to get Plan B (even though you weren't the one to have sex with her)
3) Other acts that a boy friend/girlfriend would do minus the sexual benefits, emotional attachments and etc.
Mother: So hows Andrew doing? I'm sure hes not too happy you dumped him for Josh.
Daughter: Are you kidding?! We were never dating, he just had a bad case of Best Friend Syndrome.
by ThePetRock July 29, 2009
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(usally hapens to guys) is when the person you like is also a really good frined and they would rather be good frineds
guy talking to guy friend: hey dude i talked to amber last night about goin out and she said that she really liked me and that i was like her best friend.
guy friend: haha it sounds like you got best friend syndrom goin on
by cheeze32 January 10, 2010
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A disease that your best friend inflicts upon you when you have not seen them for at least six months. Symptoms including crying and nagging of your best friend. The only known cure for this disease is for the affected patient to see their best friend. In severe, cases, if left untreated the disease can lead to fighting among best friends.
Dude, I haven't seen my best friend in months! I'm gonna get best friend withdrawal syndrome!
by ballet12 March 28, 2011
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