A more polite and less offensive word meaning asshole or butthole. The word originated from the general misuse of farm animals.

Auburn fans being assholes. Barn raised assholes.

Her vagina or butthole (depending on context) is as big as a barn.

Could refer to a girl from Barnard College. In reference to how easy it is to get access to their holes or to the fact that the school is full of whores.

To be barnholed: To be hit when you least expect it, but still make a profit.