Pronounced A.M.F.Yo.Yo.

Adios Mother Fucker You're On Your Own
Carl: Hey John can you help me with this before you clock out?
John: AMFYOYO
by Radio Rahem May 10, 2010
Get a AMFYOYO mug for your dog Paul.
AMFYOYO or Adiós Motherfucker You're On Your Own! is used when your parental, avuncular, familial, or tutelary entity etc. has had enough of your shit, and consequently kicks you to the curb.
Mom: Hey sweetie, your father and I are going for Mexican tonight and shan't be troubled by your antics!
Offspring: But what should I do for dinner?
Parentals: AMFYOYO!
by moolato99 December 11, 2017
Get a AMFYOYO mug for your Uncle Jerry.
AMF - adios mother f--ker
YOYO - you're on your own
No way I'm taking heat for your stupid decision ... AMFYOYO ... I'm out of here!
by 'net user since 1980 May 01, 2016
Get a AMFYOYO mug for your friend Larisa.