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A cyst that also has many of the same characteristics of a zit. Often seen as a large raised redish area on the skin.
Elliot wants to pop the zyst on his neck, but he really should see a doctor instead.
by DoWhat? August 25, 2009
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Jul 5 Word of the Day
"I'll be back from vacation soon. How are my fish doing?"
"Yeah, about that... 😅"

"He went to choke the chicken..."
"But that's animal abuse! How are you guys okay with this?!"
"I don't think that's what he meant by that 😅"
by wasabiMP July 08, 2016
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2
The crappy new name of RSC king/queen Mystress.
"Mystress' new name sucks...who would want the name Zyst?"
by ~ December 16, 2004
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3
n. A giant, angry, throbing, pus-filled bump; part zit, part cyst
My blind date was a nice enough guy but, I was fearful that the zyst on his face could erupt at any moment!
by tboone March 13, 2010
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