Stands for What Is Fucking Wrong. Used when someone nags a lot and you just want to tell them to get to the point. Also used when something weird happens and you don't know what is going on.

A pick me is a woman that is willing to do anything for male approval. She will embarrass or throw other women under the bus to achieve this goal. The unfortunate thing about a pick me is usually the men they are trying to seek approval from are of poor quality and treat women badly, leaving little real benefit for the pick me.