VBR stands for Various bitrate.

when you're hungover as shit after a spending a night drunk as a skunk

VBR = Very Best Regards

VBR is the acronym for the closing salutation, "Very Best Regards", commonly used at the end of letters and notes.

VBR stands for "Verify Before Retweeting." Many Twitter users retweet information that is false but convince those who agree with them to believe the false information and they themselves retweet is true, thus leading to further retweeting. VBR is a shorthand way to remind or admonish those who retweet false information that they should verify the information before retweeting it.