Usually it's telling someone to pick up a video game controler and play, it could mean pick up a lighter and hit a bong toke though, or if you to just tell someone to do something that they should already be doing, or having been told to do it already and lack the capacity to do so themselves without being yelled at.
Person 1 : "Do you wanna play video games?"

person 2 : "Yea, sure"

Person 1 : "Well then PICK UP THEM STICKS, BITCH!"
by Tower June 13, 2007
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When five Englishmen play cum on a bisquet, but the loser has to give the bisquet to his girlfreind.
Dude Brock lost the EnglishMan Stick-up and had to feed it to Alex.
by Mobsterking52 January 14, 2011
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show up with some weed
Imma pull up with a stick to the party.
I just pulled up with a stick, time to turn the fuck up.
by Cold Gangsta April 10, 2017
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taking a turkey baster and filling it up with icy hot, then shoving the turkey baster into the anus and emptying it.

"That Canadian Stick Up you gave me burned like hell."
by budajizz November 18, 2008
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A thief who uses guns/weapons to rob people. Guns are often located in their jacket or trenchcoat.
The stick up man always pawned all the jewelry he stole from his victim's.
by Chef September 01, 2015
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fresh, cool calm collective person, eloquent with words and has raw style for days
stick up kids...is a real hiphop emcee
by a Spanish poet November 29, 2014
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