to be intoxicated by alcohol.
or alcohol itself.
bruh i'm sooo twizz!!

Yo where the twizz at?!?!
by Krazy Clean January 04, 2011
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A twizz is a an individual of a frail and weak nature, similar to twink. Typically used by individuals of the uneducated variety.
Get back here you twizz, my hole is not satisfied.
by The Golden C November 06, 2017
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1. (v) To jizz on someone via twitter.
2. (n) The twitter jizz itself.
joebow696: @lizabeach05 8======D~~~~~
lizabeach05: I can't believe @joebow696 just twizzed on me!

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lizabeach05: Now my phone is sticky from all that twizz.
by dbeach January 20, 2010
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That girl i met at the bar last night turned out to be a real freak. she got twizz all over my new sheets.
by The Nate. May 23, 2012
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(Adj.) Used to describe something that is mediocre.
Sub-par
Lacking
"DUDE, THAT MOVIE RULED!"
"You kidding me? That shit was hella twizz, man."
by Kniggah June 03, 2007
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