A woman that allows a man to cum inside of her. Essentially, turning her into a delicious cream-filled pastry.

An asian who is yellow on the outside but white in the inside

A Yummy Cream filled yellow sponge cake made by Hostess

A confident, young (early twenties or younger) attractive male, often preyed upon by 'cougars'.

Twinkies have almost no defence against the experience and sexual wiles of a cougar and this can result in them feeling like a piece of meat at the end of an encounter when the cougar disposes of them.
After being trained by a cougar, the sexual technique of a twinkie will be improved significantly.

An Asian person who is culturally Western or American--yellow on the outside and white on the inside, like a Hostess Twinkie. It is the same as calling a white-acting black person an Oreo.

Youthful, only slightly muscular, relatively hairless gay man.

Slang for a VW bus (the Volkswagen Type 2, AKA Transporter).
Named for their uncanny resemblance to the cream-filled sponge cake... in shape at least. In the Slug-Bug game, Bugs are worth one slug, Twinkies are worth two, and VW Things are worth four, only because they are so rare. If you see a yellow VW bus driving down the street, you may mistake it for a giant rolling Twinkie.