Yo that crack head down the street was tweaking fighting the air earlier tripping
by Vito March 13, 2017
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Somone tripping on a meth high. They are paranoid about staying up for a week straight seeing shadow people and such.
by BigPimppin6906 November 16, 2017
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Repeatedly and obsessively engaging in a SIMPLE behavior or motion, like pulling at one's face to remove imagined objects that aren't there. Persons addicted to methamphetamine will engage in this type of compulsion. Yet, it is a myth some people subscribe to , that the behavior can extend to having sex. People high on meth can't perform anything NEARLY that complicated when they're tweaking, let alone maintain an erection or climax.
He must be tweaking like crazy, to have done that to his face!
by JB4BJ July 08, 2015
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1. To be under the effects of amphetamines, esp. crystal methamphetamine hydrochloride.

2. To be nervous or worried about something, esp. the presence of law-enforcement personnel.
1. Dude I took a fat hit of some dank ice and I'm tweaking balls!

2. Dude I got pulled over with an o in my glove compartment and I was tweaking balls!
by Bri90 January 28, 2010
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