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(v) To be high on amphetamine.
"We be tweakin, like every single weekend, we be tweekin."

"Last night I danced for 10 hours, I was tweakin hard."
by saeed October 20, 2003
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8
Acting senseless or saying random things for no apparent reason or either under the influence of marijuana.
"Man, Janet is high and she tweakin' hard."
by THA.ONE April 30, 2009
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9
1) to be high on stimulant supplements(vitamins) or drugs.

2) to be hyperactive.
1) sugar, caffeine, monster drinks, sugar, earl gray tea, amphetamine, methamphetamine are examples of commonly used stimulants that can cause a person to be tweakin. They can become fast-moving, jittery and if on meth violently jumpy or shaky (trembling)

2) ADD/ADHD, natural high, sugar high, caffeine high can cause tweakin (hypetactivity) where you'll just be all over t he place moving fast.

when someone is hyperactive it doesnt mean they are under the influence of methamphetamine where meth high causes similar behaviour but is a different kind of hyper.
by skaterjack October 06, 2006
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1. Someone that is on meth/speed
2. Someone could be called one for talking alot, pacing or moving alot or doing a task with an unusual amount of persistence, most of the time at unusual times late at night/early morning
3. You wont catch this person sleeping or eating. all though the food still looks good..
"Hey man uve been cleaning them rims for like six hours now and your on the second wheel, You tweakin?" (this is at 6 in the morning on a saturday after staying up all night, He sure was.)
by Cowshit101 June 02, 2009
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12
when you buck on somebody or think somebody thinks youre always thinking about them.
that bitch was tweakin' on the haunting of conneticut she thank somebody always tryna haunt her ass.
by pinkmonkey August 29, 2009
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13
Seeing Change Within Oneself, and achieving goals that will make their life better.

Doing Any kind of action that can make your life or someone else's life better.

Derives from the Company Tweaklife
If you gradually are doing better in school, your Tweakin'.

One do charitable work, your Tweakin' for making someone else's day better and helping them.
by Head Tweaker' February 28, 2011
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