20 Dollars worth of weed, a 20 sack of weed
Boy 1: Want to buy this twamp?
Boy 2: Nah man i got an 8th at home.
Boy 1: aight, Peace
by bigremo907 March 31, 2007
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formal definition: one gram of marijuana costing $20.

other uses: often used to refer to sack (of any size) costing $20. and sometimes to refer to a 20 dollar bill.
Pancho's been paying a twamp for them twamps. Guess no one told him 'bout them eighters or better yet them nor cal half eighters at a 20 spot. fool needa recanize.
by Androp September 24, 2006
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The sketchiest party house at Colorado College.

Origins may be from TWAT + SWAMP = TWAMP, or supposedly a reference to some sort of mold growing there. They always throw down Wednesday nights, and you'll be sure to see lots of freshmen sluts wasted out of their minds. An experience everyone must have at least once.
Person 1: You goin to The Twamp tonight??

Person 2: Nah, I don't want an STD.
by toastedbutter March 25, 2010
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Someone who is a Twat and a Tramp.
John: “Callum is a twat”
Harry: “Na Callum is a twamp
John: “Niceee
by Punjarbi February 21, 2019
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